Human immunodeficiency virus (HIV) infects CD4+T cells leading to a progressive decline in CD4 cell count, increasing immunodeficiency and vulnerability to infection, and suboptimal responses to vaccines. Use of antiretroviral therapy(ART) to reducevirus replicationandimproveCD4counts to 200cells/mm3 or higher,preferablyabove 400cells/mm3, isrecommendedto improvetheresponse to all vaccines.

For children aged under 18 years, please refer to the current Immunisation Handbook.

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