PCV10 (Synflorix) vaccine schedules | Immunisation Advisory Centre

PCV10 (Synflorix) vaccine schedules

IMPORTANT INFORMATION:

Three doses of PCV10 before 12 months of age is equivalent to:

Two doses of PCV10 given 8 weeks apart starting under 7 months of age and finishing under 12 months of age,^♦ or
Two doses of PCV10 given 4 weeks apart starting 7–11 months of age and finishing under 12 months of age.^♦

^♦Receipt of the infant doses is about best protection during the first year of life:

All children who received a complete course of infant PCV10 doses need a PCV10 booster dose when aged 12–59 months for best protection until they are aged 5 years.
All children who did not receive a complete course of infant PCV10 doses need two PCV10 doses given 8 weeks apart when aged 12–59 months for best protection until they are aged 5 years.

PCV10 – On-time immunisation for infants aged under 12 months
No PCV10 doses	Give PCV10 at 6 weeks and 5 months Give PCV10 booster dose in the second year of life
PCV10 given at 6 weeks	Give PCV10 at 5 months Give PCV10 booster dose in the second year of life
PCV10 given at 6 weeks and 3 months	Give PCV10 at 5 months (as gap between on-time 6 weeks and 3 months immunisation is less than 8 weeks) Give PCV10 booster dose in the second year of life
PCV10 given at 6 weeks and 5 months	Give PCV10 booster dose in the second year of life
PCV10 given at 6 weeks, 3 months and 5 months	Give PCV10 booster dose in the second year of life

PCV10 – Catch-up immunisation for infants aged under 12 months
No PCV10 doses	Give two PCV10 doses 8 weeks apart Give PCV10 booster dose in the second year of life (at least 4 weeks after second dose)
One PCV10 dose	Give second PCV10 dose at least 8 weeks after the first Give PCV10 booster dose in the second year of life (at least 4 weeks after second dose)
Two PCV10 doses given aged 6 months or younger with less than 8 weeks between doses	Give third PCV10 dose at least 4 weeks after the second. Give PCV10 booster dose in the second year of life (at least 4 weeks after third dose)
Two PCV10 doses given aged 7–11 months with 4 weeks or longer between doses	Give PCV10 booster dose in the second year of life (preferably at least 8 weeks after the second dose but can be 4 weeks if this brings the child in line with the Schedule)
Two PCV10 doses given with 8 weeks or longer between doses	Give PCV10 booster dose in the second year of life (at least 4 weeks after second dose)

PCV10 – Catch-up immunisation for children aged 12–59 months
No PCV10 doses		Give two PCV10 doses 8 weeks apart
First PCV10 given aged 6 months or younger	One PCV10 dose	Give two PCV10 doses 8 weeks apart
	Two PCV10 doses with less than 8 weeks between doses	Give two PCV10 doses 8 weeks apart starting at least 4 weeks after the second dose
	Two PCV10 doses with 8 weeks or longer between doses	Give one PCV10 dose at least 4 weeks after the second dose
	Three PCV10 doses	Give one PCV10 dose at least 4 weeks after the third dose
First PCV10 given aged 7–11 months	One PCV10 dose	Give two PCV10 doses 8 weeks apart starting at least 4 weeks after the first dose
	Two PCV10 doses with 4 weeks or longer between doses	Give one PCV10 dose at least 4 weeks after the second dose
First PCV10 given aged 12 months or older	One PCV10 dose	Give one PCV10 dose at least 8 weeks after the first dose
	Two PCV10 doses with 8 weeks or longer between doses	No more PCV10 doses required

Last updated: Oct 2020